On February 2, President Biden announced the renewal of the Cancer Moonshot initiative that he first launched in 2016 when he was vice president. New goals include improving living with and surviving cancer and reducing cancer death rates over the next 25 years by at least 50%. Addressing inequities in access to diagnostics and treatment is an element of the initiative. For the past two decades, Delaware has worked on reducing racial disparities by funding universal cancer screening and treatment from tobacco settlement funds. The state uses data to identify areas with low screening rates and deploys navigators to reach out to people and to help remove barriers to testing and treatment. Delaware’s overall death rate from cancer has dropped to the 15th highest in the country from the second highest.