In the midst of a nationwide increase in lawsuits seeking injunctions against state vaccination mandates, a three-judge panel of the First Circuit upheld Maine's vaccination mandate for healthcare workers set to begin October 29. Appellants originally filed this lawsuit alleging that the Maine vaccination mandate violated their rights under the Free Exercise Clause, Supremacy Clause, Equal Protection Clause, and 42 U.S.C. § 1985. Maine currently prohibits any religious or philosophical exemptions to state vaccination requirements. Following the First Circuit's ruling on October 19, appellants filed a request for preliminary injunction with the U.S. Supreme Court.