After more than a year of formal clinical affiliation, Western Maryland Health System (WMHS) signed a binding integration and affiliation agreement with University of Pittsburgh Medical Center (UPMC), one of the nation’s largest integrated health care providers and insurers. The agreement took effect on February 1. Both UPMC and the WMHS Foundation have committed to making certain capital investments and to upgrading facilities in the western Maryland region to help ensure UPMC Western Maryland continues to provide state-of-the-art care and maintains its position as one of the largest employers in the region.