The Pew Charitable Trusts reports that men have a rate of substance dependence (SUD) that is twice that of women and that men are also more likely to experience an opioid overdose. “Trauma is an important risk factor for the development of an SUD in both men and women, though the impact appears to be more significant in men,” they report. Rates of suicide are almost four times greater for men than for women, although substances are commonly found in both males and females who commit suicide. The study calls on health care systems to focus on screening and referrals for SUD and mental health treatment including behavioral health therapies.