On April 15, 2025, President Trump signed the Executive Order titled “Lowering Drug Prices by Once Again Putting Americans First,” aiming to reduce prescription drug costs and reform Medicare payment structures. This Order has several implications for physicians.
First, Section 5 of the Executive Order directs the Secretary of the Department of Health and Human Services to survey hospital acquisition costs for outpatient drugs and propose appropriate adjustments to Medicare payments. This initiative aims to align Medicare reimbursements more closely with actual drug acquisition costs, consistent with the 340B program and budget neutrality standards. The initiative could impact Medicare reimbursement to physicians who administer drugs in outpatient settings.